Queries with parameter sensitive plans can perform poorly when an inappropriate query plan is used.
Even if your statistics are up to date, parameter sensitive plans can be caused by skewed data,
so performing a data skew analysis can identify which filter columns might be involved in poor query plans.
I’ve adapted the code found here into a SQL Server stored procedure that can be run across an entire database, a schema, a single table or just a single column.
It should be relatively easy to convert this to other RDBMS.
Here’s an example of the output when run on the Stackoverflow 2013 downloadable database (approximately 50GB):
