MSDN and Microsoft.com are full of great learning resources, but it’s not always obvious what’s available. Here’s a great series of webcasts Architecting Modern Desktop Apps in .NET by Dr. Joe Hummel (recorded third quarter 2005), describing the design and development of smart client applications.
There is also a series on Modern Software Development Using C#: Develop in .NET (with a equivalent series for VB.NET) at the same URL.
You will need to sign in to MS Passport to download these webcasts (and the 2005 offline player) and go through what seems like a ridulous number of clicks to download a single webcast (Microsoft: when are you going to make this processs easier, say download a complete series???). Who said the road to continuous improvement was supposed to be easy!